Carboxymethylcellulose CMC


Or methylcellulose carboxylic, CMC, or E466

Or cellulose gum, Sodium CMC, cekol, or Blanose

It has many types that differ according to the group associated with cellulose, such as:

Carboxymethylcellulose CMC

Hydroxyethyl cellulose or HEC (telose)

Hydroxy-methylcellulose HMC

Hydroxypropyl methylcellulose HPMC

Hydroxy-methylethylcellulose HMEC

Methylcellulose MC

Ethylcellulose EC

Carboxymethylcellulose, or CMC, is one of the most important cellulose derivatives and the most widely used in the food and detergents industries, and it is a soft, light white substance. And we treat it like Tylose.

CMC is used as a stabilizer for emulsions in water-based coatings (paints), papermaking, and toothpastes. Because it is non-toxic, CMC is widely used in food and cosmetic products and in the pharmaceutical industries as a binding agent in tablets, fixative agent, suspension agent, viscosity agent and It is used in materials that help with self-adhesion to the bone (orthosis), in wound care, and in skin patches because it absorbs materials coming out of wounds.

CMC is non-toxic, non-abrasive, and 7% can be used in some materials

Carboxymethylcellulose CMC is a polymer that is made from the reaction of cellulose materials with acetic acid (acetic acid) in the presence of an alkaline substance as a catalyst for the reaction and results in a 60% carboxymethylcellulose CMC and 40% table salt, sodium chloride and sodium glycolite.

This is done in several stages, starting with soaking cellulose materials in large tanks containing cystic and keeping soaking for several days, then adjusting by concentrated vinegar acid until PH = 7, then we add ethanol or methanol and then dehydrate the material.

The sodium salt of carboxymethylcellulose has pharmaceutical uses as a coating agent, dilator in tablets and preservatives, binder in tablets, stabilizing agent, suspension agent, viscosity agent.

High concentrations of between 4-6% of these solutions are used, with a medium viscosity. They are used to prepare gels and ointments, and they usually contain glycerin to prevent them from drying out.

Stabilizing agent, suspending agent, disintegrating into tablets and portfolios, viscosity factor.

The primary use of this substance is in the preparation of tablets, where it is used as a binder and as an expanding and dissolving agent. Although this substance is not dissolved in water, it is effective as a disintegrator in tablets, as it is produced and increases in volume significantly upon contact with water. Concentrations of around 15% of this substance are used in the preparation of tablets, as the concentrations greater than that reduce the hardness of the compressor.


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